
Technological Advances in Renal Replacement Therapy
An ideal form of renal replacement therapy would mimic the kidneys completely. It would remove solutes with a molecular weight spectrum similar to that of the kidneys; would remove water and solutes on the basis of individual patient needs; and would be bio-compatible, wearable, and ideally implantable. Nissenson and colleagues have proposed the human nephron filter (HNF) as a novel mode of RRT for patients with ESRD. The HNF consists of two membranes that operate in series within one cartridge….